PUBLICATIONS

ORIGINAL PAPERS

      2021
      Shinoda, H., Taguchi, Y., Nakagawa, R., Makino, A., Okazaki, S., Nakano, M., Muramoto, Y., Takahashi, C., Takahashi, I., Ando, J., Noda, T., *Nureki, O., *Nishimasu, H., & *Watanabe, R.
      “Amplification-free RNA detection with CRISPR-Cas13”
      Commun Biol (2021)


      2020
      Soga, N., Ota, A., Nakajima, K., Watanabe, R., Ueno, H., & *Noji, H.
      “Monodisperse Liposomes with Femtoliter Volume Enable Quantitative Digital Bioassays of Membrane Transporters and Cell-Free Gene Expression”
      ACS Nano (2020)

      Sakamoto, S., *Komatsu, T., *Watanabe, R., Zhang, Y., Inoue, T., Kawaguchi, M., Nakagawa, H., Ueno, T., Okusaka, T., Honda, K., *Noji, H., & *Urano, Y.
      “Multiplexed single-molecule enzyme activity analysis for counting disease-related proteins inbiological samples”
      Sci Adv (2020) 6, eaay0888


      2018
      *Watanabe, R., Komatsu, T., Sakamoto, S., Urano, Y., & *Noji, H.
      “High-throughput single-molecule bioassay using micro-reactor arrays with a concentration gradient of target molecules”
      Lab Chip (2018) 18, 2849-2853

      Baba, K., Yoshida, W., Toriyama, M., Shimada, T., Manning, C., Saito, M., Kohno, K., Trimmer, J., Watanabe, R., & *Inagaki, N.
      “Gradient-reading and mechano-effector machinery for netrin-1–induced axon guidance”
      eLife (2018) 7, e34593

      Moriizumi, Y., *Tabata, KV, Watanabe, R., Doura, T., Kamiya, M., Urano, Y., & *Noji, H.
      “Hybrid cell reactor system from Escherichia coli protoplast cells and arrayed lipid bilayer chamber device”
      Sci Rep (2018) 8, 11757

      *Watanabe, R., Sakuragi, T., *Noji, H., & *Nagata, S.
      “Single molecule analysis of phospholipid scrambling by TMEM16F”
      Proc Natl Acad Sci USA (2018b) 115, 3066-3071

      Abe, K., Katsuno, H., Toriyama, M., Baba, K., Mori, T., Hakoshima, T., Kanemura, Y., Watanabe, R., & *Inagaki, N.
      “Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis”
      Proc Natl Acad Sci USA (2018a) 115, 2764-2769

      *Watanabe, R., Soga, N., Ohdate, S., & *Noji, H.
      “Single molecule analysis of membrane transporter activity by using a microsystem”
      Methods Mol Biol (2018) 1700, 321-330

      *Watanabe, R., Genda, M., Kato-Yamada, Y., & *Noji, H.
      “Essential role of the epsilon subunit for reversible chemo-mechanical coupling in F1-ATPase”
      Biophys J (2018) 114, 178-187

      Tamiya, Y., Watanabe, R., Noji, H., *Li, C., & *Komatsuzaki, T.
      “Effects of non-equilibrium angle fluctuation on F1-ATPase kinetics induced by temperature increase”
      Phys Chem Chem Phys (2018) 20, 1872-1880


      2016
      *Watanabe, R., Soga, N., Hara, M., & *Noji, H.
      “Arrayed water-in-oil droplet bilayers for membrane transport analysis”
      Lab Chip (2016) 16, 3043-3048

      *Watanabe, R., Soga, N., & *Noji, H.
      “Novel nano-device to measure voltage-driven membrane transporter activity”
      IEEE Trans Nanotechnol (2016) 15, 70-73

      *McMiillan, D. G., Watanabe, R., Ueno, H., Cook, G. M., & *Noji, H.
      “Biophysical Characterization of a Thermoalkaliphilic Molecular Motor with a High Stepping-Torque Gives Insight into Evolutionary ATP Synthase Adaptation”
      J Biol Chem (2016) 291, 23965-23977


      2015
      Li, C. B., Ueno, H., Watanabe, R., Noji, H., & *Komatsuzaki, T.
      “ATP hydrolysis assists Phosphate release and promotes reaction ordering in F1-ATPase”
      Nat Commun (2015) 6, 10223

      Soga, N., *Watanabe, R., & *Noji, H.
      “Attolitre-sized lipid bilayer chamber array for rapid detection of single transporters”
      Sci Rep (2015) 5, 11025

      Watanabe, R., Koyasu, K., You, H., Tanigawara, M., & *Noji, H.
      “Torque transmission mechanism via DELSEED loop of F1-ATPase”
      Biophys J (2015) 108, 1144-52

      Yukawa, A., *Watanabe, R., & *Noji, H.
      “Effects of an ATP analogue, adenosine 5'-[α-thio]triphosphate, on F1-ATPase rotary catalysis, torque generation, and inhibited intermediated formation”
      Biochem Biophys Res Commun (2015) 458, 515-9

      Yukawa, A., Iino, R., Watanabe, R., Hayashi, H., & *Noji, H.
      “Key Chemical Factors of Arginine Finger Catalysis of F1-ATPase Clarified by an Unnatural Amino Acid Mutation”
      Biochemistry (2015) 54, 472-80


      2014
      *Watanabe, R., Soga, N., Yamanaka, T., & *Noji, H.
      “High-throughput formation of lipid bilayer membrane arrays with an asymmetric lipid composition”
      Sci Rep (2014) 4, 7076

      Watanabe, R., Minagawa, Y., & *Noji, H.
      “Thermodynamic analysis of F1-ATPase rotary catalysis using high-speed imaging”
      Protein Sci (2014) 23, 1773-1779

      *Watanabe, R., Soga, N., Fujita, D., Tabata, K. V., Yamauchi, L., Kim, SH., Asanuma, D., Kamiya, M., Urano, Y., *Suga, H., & *Noji, H.
      “Arrayed lipid bilayer chambers allow single-molecule analysis of membrane transporter activity”
      Nat Commun (2014b) 5, 4519

      Watanabe, R., Matsukage, Y., Yukawa, A., Tabata, K. V., & *Noji, H.
      “Robustness of the Rotary Catalysis Mechanism of F1-ATPase”
      J Biol Chem (2014) 289, 19331-19340

      Arai, HC., Yukawa, A., Iwatate, RJ., Kamiya, M., Watanabe, R., Urano, Y., & *Noji, H.
      “Torque generation mechanism of F1-ATPase upon NTP binding”
      Biophys J (2014) 107, 156-64

      Watanabe, R., & *Noji, H.
      “Characterization of the temperature-sensitive reaction of F1-ATPase by using single-molecule manipulation”
      Sci Rep (2014) 4, 4962

      Watanabe, R., & *Noji, H.
      “Timing of inorganic phosphate release modulates the catalytic activity of ATP-driven rotary motor protein”
      Nat Commun (2014a) 5, 3486


      2013
      Watanabe, R., Hayashi, K., Ueno, H., & *Noji, H.
      “Catalysis-enhancement via rotary fluctuation of F1-ATPase”
      Biophys J (2013) 105, 2385-91

      Watanabe, R., Tabata, KV., Iino, R., Ueno, H., Iwamoto, M., Oiki, S., & *Noji, H.
      “Biased Brownian stepping rotation of FoF1-ATP synthase driven by proton motive force”
      Nat Commun (2013) 4, 1631


      2012
      Tanigawara, M., Tabata, KV., Ito, Y., Ito, J., Watanabe, R., Ueno, H., Ikeguchi, M., & *Noji, H.
      “Role of the DELSEED Loop in Torque Transmission of F1-ATPase”
      Biophys J (2012) 103, 970-8

      You, H., Iino, R., Watanabe, R., & *Noji, H.
      “Winding single-molecule double-stranded DNA on a nanometer-sized reel”
      Nucleic Acids Res (2012) 40, e151

      Watanabe, R., Okuno, D. Sakakihara, S. Shimabukuro, K. Iino, R. Yoshida, M. & *Noji, H.
      “Mechanical modulation of catalytic power on F1-ATPase”
      Nat Chem Biol (2012) 1, 86-92


      2010
      Watanabe, R., Iino, R. & *Noji, H.
      “Phosphate release in F1-ATPase catalytic cycle follows ADP release.”
      Nat Chem Biol (2010) 6, 814-20


      2009
      Enoki, S., Watanabe, R., Iino, R. & *Noji, H.
      “Single-molecule study on the temperature-sensitive reaction of F1-ATPase with a hybrid F1 carrying a single beta(E190D).”
      J Biol Chem (2009) 284, 23169-76


      2008
      Watanabe, R., Iino, R., Shimabukuro, K., Yoshida, M. & *Noji, H.
      “Temperature-sensitive reaction intermediate of F1-ATPase.”
      EMBO Rep (2008) 9, 84-90

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